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Protein General Information |
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Full Name |
Cytoplasmic protein NCK2 (NCK2)
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UniProt ID |
NCK2_HUMAN
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Gene Name |
NCK2
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Gene ID |
8440
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Interacting TTD Target Information |
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Interacting Successful Target(s) |
Epidermal growth factor receptor (EGFR) |
Target Info
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PPI Info
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[1] |
Interacting Clinical trial Target(s) |
Wiskott-Aldrich syndrome protein (WAS) |
Target Info
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PPI Info
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[2] |
Interacting Literature-reported Target(s) |
PAK-1 protein kinase (PAK1) |
Target Info
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PPI Info
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[3] |
References |
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REF 1 |
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat Methods. 2014 May;11(5):585-92.
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REF 2 |
Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics. Nat Commun. 2013;4:2863.
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REF 3 |
The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals. Nature. 2001 Sep 13;413(6852):174-9.
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