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Protein General Information (TTD Target) |
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Full Name |
Ribosomal protein S6 kinase alpha-3 (RSK3)
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Patented-recorded
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Target Info
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UniProt ID |
KS6A3_HUMAN
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Gene Name |
RPS6KA3
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Gene ID |
6197
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Interacting TTD Target Information |
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Interacting Successful Target(s) |
Fyn tyrosine protein kinase (FYN) |
Target Info
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PPI Info
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[1] |
Interacting Clinical trial Target(s) |
Extracellular signal-regulated kinase 2 (ERK2) |
Target Info
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PPI Info
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[2] |
Phosphoinositide dependent protein kinase-1 (PDPK1) |
Target Info
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PPI Info
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[3] |
References |
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REF 1 |
Epidermal growth factor stimulates RSK2 activation through activation of the MEK/ERK pathway and src-dependent tyrosine phosphorylation of RSK2 at Tyr-529. J Biol Chem. 2008 Feb 22;283(8):4652-7.
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REF 2 |
Toward an understanding of the protein interaction network of the human liver. Mol Syst Biol. 2011 Oct 11;7:536.
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REF 3 |
A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1. EMBO J. 2000 Jun 15;19(12):2924-34.
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