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| Protein General Information (TTD Target) |
Top |
| Full Name |
Integrin alpha-5 (ITGA5)
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Clinical trial
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Target Info
|
| UniProt ID |
ITA5_HUMAN
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| Gene Name |
ITGA5
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| Gene ID |
3678
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| References |
Top |
| REF 1 |
Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway. Cancer Res. 2006 Jan 15;66(2):775-83.
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| REF 2 |
Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. Sci Signal. 2009 Sep 8;2(87):ra51.
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| REF 3 |
Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes. Dev Cell. 2010 Jul 20;19(1):148-59.
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| REF 4 |
Divalent cations differentially regulate integrin alphaIIb cytoplasmic tail binding to beta3 and to calcium- and integrin-binding protein. J Biol Chem. 1999 Jun 11;274(24):17257-66.
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