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| Protein General Information (TTD Target) |
Top |
| Full Name |
IL-1 receptor-associated kinase 4 (IRAK4)
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Clinical trial
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Target Info
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| UniProt ID |
IRAK4_HUMAN
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| Gene Name |
IRAK4
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| Gene ID |
51135
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| Interacting TTD Target Information |
Top |
| Interacting Patented-recorded Target(s) |
IL-1 receptor-associated kinase 1 (IRAK1) |
Target Info
|
PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
Myeloid differentiation primary response protein MyD88 (MYD88) |
Target Info
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PPI Info
|
[2] |
| References |
Top |
| REF 1 |
Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J Exp Med. 2003 Jan 20;197(2):263-8.
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| REF 2 |
A20-binding inhibitor of NF-B (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein activation and protects from inflammatory disease. Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):E998-1006.
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