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| Protein General Information (TTD Target) |
Top |
| Full Name |
Hypoxia-inducible factor 2 alpha (HIF-2A)
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Successful
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Target Info
|
| UniProt ID |
EPAS1_HUMAN
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| Gene Name |
EPAS1
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| Gene ID |
2034
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| References |
Top |
| REF 1 |
Identification of the hypoxia-inducible factor 2 nuclear interactome in melanoma cells reveals master proteins involved in melanoma development. Mol Cell Proteomics. 2013 Mar;12(3):736-48.
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| REF 2 |
Cancer-causing mutations in a novel transcription-dependent nuclear export motif of VHL abrogate oxygen-dependent degradation of hypoxia-inducible factor. Mol Cell Biol. 2008 Jan;28(1):302-14.
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| REF 3 |
Erythrocytosis-associated HIF-2alpha mutations demonstrate a critical role for residues C-terminal to the hydroxylacceptor proline. J Biol Chem. 2009 Apr 3;284(14):9050-8.
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| REF 4 |
Opposite functions of HIF- isoforms in VEGF induction by TGF-1 under non-hypoxic conditions. Oncogene. 2011 Mar 10;30(10):1213-28.
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