Protein-Protein Interaction Details
Protein General Information | Top | ||||
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Full Name | Elongin-C (ELOC) | ||||
UniProt ID | ELOC_HUMAN | ||||
Gene Name | TCEB1 | ||||
Gene ID | 6921 |
Interacting TTD Target Information | Top | ||||
---|---|---|---|---|---|
Interacting Clinical trial Target(s) | Hypoxia-inducible factor 1 alpha (HIF-1A) | Target Info | PPI Info | [1] | |
Tumor expressed melanoma antigen (PRAME) | Target Info | PPI Info | [5] | ||
Interacting Patented-recorded Target(s) | von Hippel-Lindau disease tumor suppressor (VHL) | Target Info | PPI Info | [2] | |
Interacting Literature-reported Target(s) | Cullin-3 (CUL-3) | Target Info | PPI Info | [3] | |
Suppressor of cytokine signaling 3 (SOCS3) | Target Info | PPI Info | [4] |
References | Top | ||||
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REF 1 | MCM proteins are negative regulators of hypoxia-inducible factor 1. Mol Cell. 2011 Jun 10;42(5):700-12. | ||||
REF 2 | Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509. | ||||
REF 3 | Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. Cell. 2010 Dec 10;143(6):951-65. | ||||
REF 4 | Zinc chelation inhibits HIV Vif activity and liberates antiviral function of the cytidine deaminase APOBEC3G. FASEB J. 2007 Jan;21(1):217-22. | ||||
REF 5 | The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters. EMBO J. 2011 Aug 5;30(18):3786-98. |
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