Protein-Protein Interaction Details
| Protein General Information (TTD Target) | Top | ||||
|---|---|---|---|---|---|
| Full Name | Melanoma inhibitor of apoptosis protein (ML-IAP) | Patented-recorded | Target Info | ||
| UniProt ID | BIRC7_HUMAN | ||||
| Gene Name | BIRC7 | ||||
| Gene ID | 79444 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Clinical trial Target(s) | Caspase-3 (CASP3) | Target Info | PPI Info | [1] | |
| Caspase-9 (CASP9) | Target Info | PPI Info | [2] | ||
| Cellular inhibitor of apoptosis 1 (BIRC2) | Target Info | PPI Info | [3] | ||
| X-linked inhibitor of apoptosis protein (XIAP) | Target Info | PPI Info | [3] | ||
| Interacting Patented-recorded Target(s) | Melanoma inhibitor of apoptosis protein (ML-IAP) | Target Info | PPI Info | [4] | |
| Interacting Literature-reported Target(s) | Direct IAP-binding protein with low pI (DIABLO) | Target Info | PPI Info | [5] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Overexpression of the truncated form of Livin reveals a complex interaction with caspase-3. Int J Oncol. 2013 Jun;42(6):2037-45. | ||||
| REF 2 | Livin, a novel inhibitor of apoptosis protein family member. J Biol Chem. 2001 Feb 2;276(5):3238-46. | ||||
| REF 3 | Role of melanoma inhibitor of apoptosis (ML-IAP) protein, a member of the baculoviral IAP repeat (BIR) domain family, in the regulation of C-RAF kinase and cell migration. J Biol Chem. 2012 Aug 17;287(34):28445-55. | ||||
| REF 4 | BIRC7-E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer. Nat Struct Mol Biol. 2012 Sep;19(9):876-83. | ||||
| REF 5 | Livin modulates the apoptotic effects of vesicular stomatotitis virus in lung adenocarcinoma. Int J Oncol. 2015 Nov;47(5):1775-82. | ||||
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