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Protein General Information (TTD Target) |
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Full Name |
Beta-adrenergic receptor kinase 1 (GRK2)
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Patented-recorded
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Target Info
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UniProt ID |
ARBK1_HUMAN
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Gene Name |
GRK2
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Gene ID |
156
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Interacting TTD Target Information |
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Interacting Successful Target(s) |
Adrenergic receptor beta-2 (ADRB2) |
Target Info
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PPI Info
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[1] |
Interacting Clinical trial Target(s) |
Ubiquitin-protein ligase E3 Mdm2 (MDM2) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
The scaffold protein gravin (cAMP-dependent protein kinase-anchoring protein 250) binds the beta 2-adrenergic receptor via the receptor cytoplasmic... J Biol Chem. 2001 Jun 29;276(26):24005-14.
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REF 2 |
The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization. Glia. 2015 Dec;63(12):2327-39.
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