Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T13616 Target Info
Target Name Integrin-linked protein kinase 1 (ILK)
Synonyms P59ILK; Integrin-linked protein kinase; Integrin-linked kinase; ILK2; ILK1; ILK-2; ILK-1; Beta-integrin-linked kinase; 59 kDa serine/threonine-protein kinase; 59 kDa serine/threonine protein kinase
Target Type Patented-recorded Target
Gene Name ILK
Biochemical Class Kinase
UniProt ID
ILK_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US8754233
Title Pyrazolylbenzothiazole derivatives and their use as therapeutic agents
Abstract Topical formulations and method of using the same are provided. The topical formulation comprises a pyrazolylbenzothiazole derivative of the following formula (1) wherein X, R1, R2, R3 and R4 are described herein.
Applicant(s) Dermira (Canada), Inc.
Representative Drug(s) D0Q7KI Drug Info IC50 = 20 nM Click to Show More [1]
2 D0FL7J Drug Info IC50 = 200 nM [1]
3 D09CNM Drug Info IC50 = 4000 nM [1]
Patent ID US8754233
Title Pyrazolylbenzothiazole derivatives and their use as therapeutic agents
Abstract Topical formulations and method of using the same are provided. The topical formulation comprises a pyrazolylbenzothiazole derivative of the following formula (1) wherein X, R1, R2, R3 and R4 are described herein.
Applicant(s) Dermira (Canada), Inc.
Representative Drug(s) D0Q7KI Drug Info IC50 = 20 nM Click to Show More [1]
2 D0FL7J Drug Info IC50 = 200 nM [1]
3 D09CNM Drug Info IC50 = 4000 nM [1]
Patent ID US8754233
Title Pyrazolylbenzothiazole derivatives and their use as therapeutic agents
Abstract Topical formulations and method of using the same are provided. The topical formulation comprises a pyrazolylbenzothiazole derivative of the following formula (1) wherein X, R1, R2, R3 and R4 are described herein.
Applicant(s) Dermira (Canada), Inc.
Representative Drug(s) D0Q7KI Drug Info IC50 = 20 nM Click to Show More [1]
2 D0FL7J Drug Info IC50 = 200 nM [1]
3 D09CNM Drug Info IC50 = 4000 nM [1]
References  Top
REF 1 Pyrazolylbenzothiazole derivatives and their use as therapeutic agents. US8754233.

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