Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0FL7J
|
|||
| Drug Name |
US8754233, (4-Benzothiazol-2-yl-1H-pyrazol-3-yl)-[2-(1H-imidazol-4-yl)-ethyl]-amine
|
|||
| Synonyms |
SCHEMBL686607; CHEMBL3680986; BDBM123923; US8754233, (4-Benzothiazol-2-yl-1H-pyrazol-3-yl)-[2-(1H-imidazol-4-yl)-ethyl]-amine
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C15H14N6S
|
|||
| Canonical SMILES |
C1=CC=C2C(=C1)N=C(S2)C3=C(NN=C3)NCCC4=CN=CN4
|
|||
| InChI |
1S/C15H14N6S/c1-2-4-13-12(3-1)20-15(22-13)11-8-19-21-14(11)17-6-5-10-7-16-9-18-10/h1-4,7-9H,5-6H2,(H,16,18)(H2,17,19,21)
|
|||
| InChIKey |
SKFIGKZRFZMUKR-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Integrin-linked protein kinase 1 (ILK) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Integrin-linked protein kinase 1 (ILK) | Target's Patent Info | [1] | |
| NetPath Pathway | TCR Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Panther Pathway | Integrin signalling pathway | |||
| Pathway Interaction Database | Osteopontin-mediated events | |||
| Integrin-linked kinase signaling | ||||
| Integrins in angiogenesis | ||||
| Reactome | Localization of the PINCH-ILK-PARVIN complex to focal adhesions | |||
| WikiPathways | Eukaryotic Transcription Initiation | |||
| Focal Adhesion | ||||
| Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| Integrin-mediated Cell Adhesion | ||||
| Cell junction organization | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pyrazolylbenzothiazole derivatives and their use as therapeutic agents. US8754233. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.