Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q7KI
|
|||
| Drug Name |
US8754233, 2-(3-Amino-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-sulfonic acid amide
|
|||
| Synonyms |
SCHEMBL687220; CHEMBL3639798; BDBM123930; US8754233, 2-(3-Amino-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-sulfonic acid amide
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C10H8FN5O2S2
|
|||
| Canonical SMILES |
C1=C2C(=CC(=C1F)S(=O)(=O)N)SC(=N2)C3=C(NN=C3)N
|
|||
| InChI |
1S/C10H8FN5O2S2/c11-5-1-6-7(2-8(5)20(13,17)18)19-10(15-6)4-3-14-16-9(4)12/h1-3H,(H3,12,14,16)(H2,13,17,18)
|
|||
| InChIKey |
MJSWBRWBMZMVTH-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Integrin-linked protein kinase 1 (ILK) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Integrin-linked protein kinase 1 (ILK) | Target's Patent Info | [1] | |
| NetPath Pathway | TCR Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Panther Pathway | Integrin signalling pathway | |||
| Pathway Interaction Database | Osteopontin-mediated events | |||
| Integrin-linked kinase signaling | ||||
| Integrins in angiogenesis | ||||
| Reactome | Localization of the PINCH-ILK-PARVIN complex to focal adhesions | |||
| WikiPathways | Eukaryotic Transcription Initiation | |||
| Focal Adhesion | ||||
| Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| Integrin-mediated Cell Adhesion | ||||
| Cell junction organization | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pyrazolylbenzothiazole derivatives and their use as therapeutic agents. US8754233. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.