Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T04831 Target Info
Target Name Tyrosine-protein kinase EIF2AK2 (p68)
Synonyms p68 kinase; Proteinkinase RNA-activated; Interferon-inducible RNA-dependent protein kinase p68; Interferon-induced, double-stranded RNA-activated protein kinase p68
Target Type Patented-recorded Target
Gene Name EIF2AK2
Biochemical Class Kinase
UniProt ID
E2AK2_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
United States Patent and Trademark Office (USPTO)
Patent ID US9650366
Title Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors
Abstract This invention is directed to a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and X are as defined herein. The compounds of Formula I are useful as receptor tyrosine kinase (RTK) inhibitors and can be used to treat such diseases as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders and metabolic diseases.
Applicant(s) ALLERGAN, INC.
Representative Drug(s) D0Z0BQ Drug Info N.A. Click to Show More [1]
2 D0QZ4B Drug Info N.A. [1]
3 D05GPF Drug Info N.A. [1]
Patent ID US9650366
Title Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors
Abstract This invention is directed to a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and X are as defined herein. The compounds of Formula I are useful as receptor tyrosine kinase (RTK) inhibitors and can be used to treat such diseases as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders and metabolic diseases.
Applicant(s) ALLERGAN, INC.
Representative Drug(s) D0Z0BQ Drug Info N.A. Click to Show More [1]
2 D0QZ4B Drug Info N.A. [1]
3 D05GPF Drug Info N.A. [1]
Patent ID US9650366
Title Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors
Abstract This invention is directed to a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and X are as defined herein. The compounds of Formula I are useful as receptor tyrosine kinase (RTK) inhibitors and can be used to treat such diseases as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders and metabolic diseases.
Applicant(s) ALLERGAN, INC.
Representative Drug(s) D0Z0BQ Drug Info N.A. Click to Show More [1]
2 D0QZ4B Drug Info N.A. [1]
3 D05GPF Drug Info N.A. [1]
References  Top
REF 1 Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors. US9650366.

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