Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0QZ4B
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| Drug Name |
US9650366, 2
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| Synonyms |
SCHEMBL17669993; LHUVPYZTQHNXRU-UHFFFAOYSA-N; BDBM308050; US9650366, 2; 1-{2-[2-amino-5-(2H-tetrazol-5-yl)pyridin-3-yl]-1-benzothien-5-yl}-3-[4-chloro-3-(trifluoromethyl)phenyl]urea; 1-(2-(2-amino-5-(2H-tetrazol-5-yl)pyridin-3-yl)benzo[b]thiophen-5-yl)-3-(4-chloro-3-(trifluoromethyl)phenyl)urea
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C22H14ClF3N8OS
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| Canonical SMILES |
C1=CC2=C(C=C1NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)C=C(S2)C4=C(N=CC(=C4)C5=NNN=N5)N
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| InChI |
1S/C22H14ClF3N8OS/c23-16-3-1-13(8-15(16)22(24,25)26)30-21(35)29-12-2-4-17-10(5-12)7-18(36-17)14-6-11(9-28-19(14)27)20-31-33-34-32-20/h1-9H,(H2,27,28)(H2,29,30,35)(H,31,32,33,34)
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| InChIKey |
LHUVPYZTQHNXRU-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosine-protein kinase EIF2AK2 (p68) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Tyrosine-protein kinase EIF2AK2 (p68) | Target's Patent Info | [1] | |
| Panther Pathway | Apoptosis signaling pathway | |||
| Pathway Interaction Database | Signaling events mediated by TCPTP | |||
| Ceramide signaling pathway | ||||
| PDGFR-beta signaling pathway | ||||
| Reactome | ISG15 antiviral mechanism | |||
| WikiPathways | Type II interferon signaling (IFNG) | |||
| Host Interactions with Influenza Factors | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| Translation Factors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors. US9650366. | |||
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