miRNA General Information
miRNA Mature ID hsa-miR-885-5p
miRNA Stemloop AC MI0005560
miRNA Stemloop ID hsa-mir-885
Sequence uccauuacacuacccugccucu
TTD Target(s) Regulated by This miRNA Insulin-like growth factor I receptor (IGF1R) Successful Target Target Info [1]
Beta-catenin (CTNNB1) Successful Target Target Info [2]
Cyclin-dependent kinase 2 (CDK2) Clinical trial Target Target Info [3]
Caspase-3 (CASP3) Clinical trial Target Target Info [4]
Protein(s) Regulated by This miRNA DNA replication licensing factor MCM5 Regulated Protein [3]
References
REF 1 p73 and IGF1R Regulate Emergence of Aggressive Cancer Stem-like Features via miR-885-5p Control. Cancer Res. 2016 Jan 15;76(2):197-205.
REF 2 miR-885-5p suppresses hepatocellular carcinoma metastasis and inhibits Wnt/-catenin signaling pathway. Oncotarget. 2016 Nov 15;7(46):75038-75051.
REF 3 MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival. Cell Death Differ. 2011 Jun;18(6):974-84.
REF 4 A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer. FASEB J. 2013 Apr;27(4):1404-12.
REF 5 MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival. Cell Death Differ. 2011 Jun;18(6):974-84.

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