miRNA General Information
miRNA Mature ID hsa-miR-409-3p
miRNA Stemloop AC MI0001735
miRNA Stemloop ID hsa-mir-409
Sequence gaauguugcucggugaaccccu
TTD Target(s) Regulated by This miRNA Proto-oncogene c-Met (MET) Successful Target Target Info [1]
Interferon-gamma (IFNG) Successful Target Target Info [2]
RAC-alpha serine/threonine-protein kinase (AKT1) Successful Target Target Info [3]
O-6-methylguanine-DNA-alkyltransferase (MGMT) Clinical trial Target Target Info [4]
Angiogenin (ANG) Literature-reported Target Target Info [5]
Fibrinogen (FGG) Literature-reported Target Target Info [6]
Suppressor of tumorigenicity 15 protein (ST15) Literature-reported Target Target Info [7]
Protein(s) Regulated by This miRNA Catenin delta-1 Regulated Protein [8]
Cohesin subunit SA-2 Regulated Protein [9]
ETS-related transcription factor Elf-2 Regulated Protein [10]
Fibrinogen alpha chain Regulated Protein [6]
Fibrinogen beta chain Regulated Protein [6]
GRB2-associated-binding protein 1 Regulated Protein [12]
PHD finger protein 10 Regulated Protein [13]
Proto-oncogene FRAT1 Regulated Protein [14]
Radixin Regulated Protein [15]
Ras suppressor protein 1 Regulated Protein [9]
Serine/threonine-protein kinase NLK Regulated Protein [16]
UDP-glucuronosyltransferase 2B17 Regulated Protein [17]
Zinc finger E-box-binding homeobox 1 Regulated Protein [18]
References
REF 1 MicroRNA-409-3p inhibits migration and invasion of bladder cancer cells via targeting c-Met. Mol Cells. 2013 Jul;36(1):62-8.
REF 2 Reduced expression of MIR409-3p in primary immune thrombocytopenia. Br J Haematol. 2013 Apr;161(1):128-35.
REF 3 miR-409-3p suppresses breast cancer cell growth and invasion by targeting Akt1. Biochem Biophys Res Commun. 2016 Jan 8;469(2):189-95.
REF 4 miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma. Oncotarget. 2016 May 10;7(19):28195-206.
REF 5 miR-409-3p inhibits HT1080 cell proliferation, vascularization and metastasis by targeting angiogenin. Cancer Lett. 2012 Oct 28;323(2):171-9.
REF 6 Regulation of fibrinogen production by microRNAs. Blood. 2010 Oct 7;116(14):2608-15.
REF 7 MicroRNA-130a regulates cell malignancy by targeting RECK in chronic myeloid leukemia. Am J Transl Res. 2016 Feb 15;8(2):955-67.
REF 8 MicroRNA-409-3p inhibits osteosarcoma cell migration and invasion by targeting catenin-1.Gene. 2016 Jun 10;584(1):83-9.
REF 9 Stromal fibroblast-derived miR-409 promotes epithelial-to-mesenchymal transition and prostate tumorigenesis.Oncogene. 2015 May 21;34(21):2690-9.
REF 10 MiR-409-3p regulates cell proliferation and tumor growth by targeting E74-like factor 2 in osteosarcoma.FEBS Open Bio. 2017 Jan 27;7(3):348-357.
REF 11 Regulation of fibrinogen production by microRNAs. Blood. 2010 Oct 7;116(14):2608-15.
REF 12 MicroRNA-409-3p suppresses colorectal cancer invasion and metastasis partly by targeting GAB1 expression.Int J Cancer. 2015 Nov 15;137(10):2310-22.
REF 13 MicroRNA-409-3p regulates cell proliferation and apoptosis by targeting PHF10 in gastric cancer.Cancer Lett. 2012 Jul 28;320(2):189-97.
REF 14 Epigenetic silencing of miR-490-3p promotes development of an aggressive colorectal cancer phenotype through activation of the Wnt/-catenin signaling pathway.Cancer Lett. 2016 Jun 28;376(1):178-87.
REF 15 MicroRNA-409 suppresses tumour cell invasion and metastasis by directly targeting radixin in gastric cancers.Oncogene. 2012 Oct 18;31(42):4509-16.
REF 16 Downregulation of microRNA-409-3p promotes aggressiveness and metastasis in colorectal cancer: an indication for personalized medicine.J Transl Med. 2015 Jun 18;13:195.
REF 17 Epigenetic regulation of steroid inactivating UDP-glucuronosyltransferases by microRNAs in prostate cancer.J Steroid Biochem Mol Biol. 2016 Jan;155(Pt A):85-93.
REF 18 MicroRNA-409-3p regulates cell invasion and metastasis by targeting ZEB1 in breast cancer.IUBMB Life. 2016 May;68(5):394-402.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.