Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0WS3T
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| Drug Name |
US10092575, Example 141
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| Synonyms |
CHEMBL4067682; SCHEMBL17225636; BDBM289653; US10092575, Example 141; 6-(2-fluoro-4-methoxybenzyl)-9-((tetrahydro-2H-pyran-4-yl)methyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one; 6-(2-Fluoro-4-methoxybenzyl)-9-((tetrahydro-2H-pyran-4-yl)methyl)-8,9,10,11-tetrahydropyrido[4'',3'':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5 (6H)-one
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C24H26FN5O3S
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| Canonical SMILES |
COC1=CC(=C(C=C1)CN2C3=C(C4=C(S3)CN(CC4)CC5CCOCC5)C6=NC=NN6C2=O)F
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| InChI |
1S/C24H26FN5O3S/c1-32-17-3-2-16(19(25)10-17)12-29-23-21(22-26-14-27-30(22)24(29)31)18-4-7-28(13-20(18)34-23)11-15-5-8-33-9-6-15/h2-3,10,14-15H,4-9,11-13H2,1H3
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| InChIKey |
FOZFBBKUKXGMND-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 1B (PDE1B) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Phosphodiesterase 1B (PDE1B) | Target's Patent Info | [1] | |
| KEGG Pathway | Purine metabolism | |||
| Calcium signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| WikiPathways | G Protein Signaling Pathways | |||
| DAG and IP3 signaling | ||||
| Opioid Signalling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Therapeutic thiophene-, furan-, and pyridine-fused azolopyrimidin-5-(6h)-ones. US10105367. | |||
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