Drug Information
Drug General Information | Top | |||
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Drug ID |
D0V8ZY
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Drug Name |
US10034861, Example 1
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Synonyms |
SCHEMBL19762512; US10034861, Example 1; BDBM278971; 5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]pyrazolo[4,3-b]pyridin-7-amine
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C21H25N7O2
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Canonical SMILES |
CCOC1=C(C=CC=N1)C2=NC3=C(C(=C2)NCC4=NN=C(O4)C)N(N=C3C)C(C)C
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InChI |
1S/C21H25N7O2/c1-6-29-21-15(8-7-9-22-21)16-10-17(23-11-18-26-25-14(5)30-18)20-19(24-16)13(4)27-28(20)12(2)3/h7-10,12H,6,11H2,1-5H3,(H,23,24)
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InChIKey |
XEBJMVLHZBRKST-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Phosphodiesterase 1B (PDE1B) | Target Info | Inhibitor | [1] |
Target's Patent Info | Phosphodiesterase 1B (PDE1B) | Target's Patent Info | [1] | |
KEGG Pathway | Purine metabolism | |||
Calcium signaling pathway | ||||
Morphine addiction | ||||
Reactome | cGMP effects | |||
G alpha (s) signalling events | ||||
WikiPathways | G Protein Signaling Pathways | |||
DAG and IP3 signaling | ||||
Opioid Signalling |
References | Top | |||
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REF 1 | 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors. US10034861. |
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