Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0T0AG
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| Former ID |
DIB019799
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| Drug Name |
EBIO
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| Synonyms |
10045-45-1; 1-Ethyl-2-benzimidazolinone; 1-EBIO; 1-ethyl-1H-benzo[d]imidazol-2(3H)-one; 1-Ethylbenzimidazolinone; 1-Ethylbenzimidazolin-2-one; 1-ethyl-1,3-dihydro-2h-benzimidazol-2-one; 2H-Benzimidazol-2-one, 1-ethyl-1,3-dihydro-; 1-Ethyl-Benzimidazolinone; UNII-M82W79SS4W; 3-ethyl-1H-benzimidazol-2-one; EINECS 233-148-1; CHEMBL452887; M82W79SS4W; CHEBI:34076; CXUCKELNYMZTRT-UHFFFAOYSA-N; 1-ethyl-2,3-dihydro-1H-1,3-benzodiazol-2-one; 1-EB10; EBIO; 1-ethyl-1,3-dihydrobenzimidazol-2-one; Tocris-1041; AC1Q2ZX3; AC1Q2ZX4
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C9H10N2O
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| Canonical SMILES |
CCN1C2=CC=CC=C2NC1=O
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| InChI |
1S/C9H10N2O/c1-2-11-8-6-4-3-5-7(8)10-9(11)12/h3-6H,2H2,1H3,(H,10,12)
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| InChIKey |
CXUCKELNYMZTRT-UHFFFAOYSA-N
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| CAS Number |
CAS 10045-45-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
854085, 3137865, 4923486, 7980361, 10219323, 11113874, 12104700, 15147028, 38562145, 43137456, 49761611, 50064056, 53787531, 57333402, 79605933, 88522474, 92148813, 103099734, 103647967, 104118732, 104380287, 105761106, 115996234, 117432347, 117432348, 117601074, 118867985, 124886973, 125725987, 126923245, 127353445, 127693326, 129127318, 131365138, 131487068, 135040213, 135650218, 137265109, 142025564, 144088855, 152200271, 160781788, 162022768, 162026032, 162282707, 163083888, 163377859, 163568596, 164820416, 169201892
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| ChEBI ID |
CHEBI:34076
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium-activated potassium channel KCa2.1 (KCNN1) | Target Info | Activator | [2] |
| Calcium-activated potassium channel KCa2.2 (KCNN2) | Target Info | Activator | [2] | |
| Calcium-activated potassium channel KCa2.3 (KCNN3) | Target Info | Activator | [2] | |
| Calcium-activated potassium channel KCa3.1 (KCNN4) | Target Info | Activator | [2] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2314). | |||
| REF 2 | Small conductance calcium-activated potassium channels: from structure to function. Prog Neurobiol. 2010 Jul;91(3):242-55. | |||
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