Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08BJR
|
|||
| Former ID |
DIB020136
|
|||
| Drug Name |
Ki-20227
|
|||
| Synonyms |
Ki 20227; Ki20227
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
||
| Formula |
C24H24N4O5S
|
|||
| Canonical SMILES |
CC(C1=NC=CS1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)OC
|
|||
| InChI |
1S/C24H24N4O5S/c1-14(23-26-9-10-34-23)27-24(29)28-17-6-5-15(11-20(17)30-2)33-19-7-8-25-18-13-22(32-4)21(31-3)12-16(18)19/h5-14H,1-4H3,(H2,27,28,29)
|
|||
| InChIKey |
SHPFDGWALWEPGS-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 623142-96-1
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
14834765, 24160801, 45292043, 80815482, 125329931, 125571010, 135685332, 135685333, 135685352, 136931825, 136959518, 137276037, 137875917, 139382726, 143499037, 152043707, 152234893, 152258204, 152344435, 160647040, 162205105, 172919149, 174561047, 178102317, 185998802, 189614654, 224053637, 230399915, 244672854, 252158098, 252215641, 252543319
|
|||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model. Mol Cancer Ther. 2006 Nov;5(11):2634-43. | |||
| REF 2 | Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol. 2011 Oct 30;29(11):1046-51. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.