Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06WJK
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| Drug Name |
US10034861, Example 164
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| Synonyms |
SCHEMBL19762485; BDBM279133; US10034861, Example 164; 5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-7-[(1-methylpyrazol-4-yl)methylsulfanyl]pyrazolo[4,3-b]pyridine
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C24H32N4O3S
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| Canonical SMILES |
CCOC1=C(C=CC=N1)C2=NC3=C(C(=C2)SCCC(=O)OCC(C)C)N(N=C3C)C(C)C
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| InChI |
1S/C24H32N4O3S/c1-7-30-24-18(9-8-11-25-24)19-13-20(32-12-10-21(29)31-14-15(2)3)23-22(26-19)17(6)27-28(23)16(4)5/h8-9,11,13,15-16H,7,10,12,14H2,1-6H3
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| InChIKey |
HVDCJFCTBUPVCE-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 1B (PDE1B) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Phosphodiesterase 1B (PDE1B) | Target's Patent Info | [1] | |
| KEGG Pathway | Purine metabolism | |||
| Calcium signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| WikiPathways | G Protein Signaling Pathways | |||
| DAG and IP3 signaling | ||||
| Opioid Signalling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors. US10034861. | |||
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