Drug Information
Drug General Information | Top | |||
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Drug ID |
D05XAT
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Drug Name |
PMID27109571-Compound-28
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Drug Type |
Small molecular drug
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Company |
F. HOFFMANN-LA ROCHE AG HOFFMANN-LA ROCHE INC
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Structure |
Download2D MOL |
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Formula |
C19H18ClFN2O3
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Canonical SMILES |
C1CCC(C1)(C(=O)O)NC(=O)NC2=C(C=CC(=C2)Cl)C3=CC=C(C=C3)F
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InChI |
1S/C19H18ClFN2O3/c20-13-5-8-15(12-3-6-14(21)7-4-12)16(11-13)22-18(26)23-19(17(24)25)9-1-2-10-19/h3-8,11H,1-2,9-10H2,(H,24,25)(H2,22,23,26)
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InChIKey |
PDTYXZFDMKYTCF-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Fatty acid-binding protein 4 (FABP4) | Target Info | Inhibitor | [1] |
Fatty acid-binding protein 5 (FABP5) | Target Info | Inhibitor | [1] | |
Target's Patent Info | Fatty acid-binding protein 4 (FABP4) | Target's Patent Info | [1] | |
Fatty acid-binding protein 5 (FABP5) | Target's Patent Info | [1] | ||
KEGG Pathway | PPAR signaling pathway | |||
NetPath Pathway | IL1 Signaling Pathway | |||
TCR Signaling Pathway | ||||
Pathway Interaction Database | AP-1 transcription factor network | |||
Reactome | Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |||
Transcriptional regulation of white adipocyte differentiation | ||||
WikiPathways | Lipid digestion, mobilization, and transport | |||
Transcriptional Regulation of White Adipocyte Differentiation |
References | Top | |||
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REF 1 | Fatty acid binding protein (FABP) inhibitors: a patent review (2012-2015).Expert Opin Ther Pat. 2016 Jul;26(7):767-76. |
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