Target and Its Patented Drug(s)

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Target General Information
Patent(s) and the Corresponding Patented Drug(s)
References
Target General Information  Top
Target ID T07217 Target Info
Target Name Fatty acid-binding protein 4 (FABP4)
Synonyms Fatty acid-binding protein, adipocyte; Adipocyte-type fatty acid-binding protein; Adipocyte lipid-binding protein; Adipocyte fatty-acid-binding protein; Adipocyte fatty binding protein; ALBP; AFABP; A-FABP
Target Type Patented-recorded Target
Gene Name FABP4
Biochemical Class Fatty acid binding protein
UniProt ID
FABP4_HUMAN
Patent(s) and the Corresponding Patented Drug(s)  Top
World Intellectual Property Organization (WIPO)
Patent ID WO2014146995
Title Urea Derivatives and Their Use As Fatty-Acid Binding Protein (Fabp) Inhibitors.
Abstract The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, W, A and B are as described herein, compositions including the compounds and methods of using the compounds.
Applicant(s) F. Hoffmann-La Roche Ag
Representative Drug(s) D01TJW Drug Info IC50 = 50 nM Click to Show More [1]
United States Patent and Trademark Office (USPTO)
Patent ID US8889683
Title Substituted Quinoxalines As Inhibitors of Fatty Acid Binding Protein.
Representative Drug(s) D0Q9LM Drug Info Kd = 0.1 nM Click to Show More [1]
Patent ID US2014029723
Title Compositions, formulations and Methods for Treating Ocular Diseases.
Representative Drug(s) D0R9RK Drug Info IC50 = 10 nM Click to Show More [1]
Patent ID US20130116234
Title Aryl-Quinoline Derivatives.
Representative Drug(s) D06JEA Drug Info IC50 = 13.2 nM Click to Show More [1]
References  Top
REF 1 Fatty acid binding protein (FABP) inhibitors: a patent review (2012-2015).Expert Opin Ther Pat. 2016 Jul;26(7):767-76.

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