Target and Its Patented Drug(s)
Target General Information | Top | ||||
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Target ID | T21507 | Target Info | |||
Target Name | Fatty acid-binding protein 5 (FABP5) | ||||
Synonyms | Psoriasis-associated fatty acid-binding protein homolog; PA-FABP; Fatty acid-binding protein, epidermal; Fatty Acid BindingProtein mal1; Epidermal-type fatty acid-binding protein; E-FABP | ||||
Target Type | Patented-recorded Target | ||||
Gene Name | FABP5 | ||||
Biochemical Class | Fatty acid binding protein | ||||
UniProt ID |
Patent(s) and the Corresponding Patented Drug(s) | Top | ||||
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World Intellectual Property Organization (WIPO) | |||||
Patent ID | WO2014146995 | ||||
Title | Urea Derivatives and Their Use As Fatty-Acid Binding Protein (Fabp) Inhibitors. | ||||
Abstract | The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, W, A and B are as described herein, compositions including the compounds and methods of using the compounds. | ||||
Applicant(s) | F. Hoffmann-La Roche Ag | ||||
Representative Drug(s) | D01TJW | Drug Info | IC50 = 3790 nM | Click to Show More | [1] |
United States Patent and Trademark Office (USPTO) | |||||
Patent ID | US2014029723 | ||||
Title | Compositions, formulations and Methods for Treating Ocular Diseases. | ||||
Representative Drug(s) | D0CT9O | Drug Info | IC50 = 20 nM | Click to Show More | [1] |
Patent ID | US20130116234 | ||||
Title | Aryl-Quinoline Derivatives. | ||||
Representative Drug(s) | D06JEA | Drug Info | IC50 = 51.2 nM | Click to Show More | [1] |
References | Top | ||||
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REF 1 | Fatty acid binding protein (FABP) inhibitors: a patent review (2012-2015).Expert Opin Ther Pat. 2016 Jul;26(7):767-76. |
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