Drug Information
Drug General Information | Top | |||
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Drug ID |
D00LVD
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Drug Name |
US10034861, Example 165
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Synonyms |
SCHEMBL19762492; BDBM279134; US10034861, Example 165; N-[[1-(difluoromethyl)pyrazol-4-yl]methyl]-5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-pyrazolo[4,3-b]pyridin-7-amine
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C30H33F2N7O2
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Canonical SMILES |
CCOC1=C(C=CC=N1)C2=NC3=C(C(=C2)N(CC4=CC=C(C=C4)OC)CC5=CN(N=C5)C(F)F)N(N=C3C)C(C)C
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InChI |
1S/C30H33F2N7O2/c1-6-41-29-24(8-7-13-33-29)25-14-26(28-27(35-25)20(4)36-39(28)19(2)3)37(16-21-9-11-23(40-5)12-10-21)17-22-15-34-38(18-22)30(31)32/h7-15,18-19,30H,6,16-17H2,1-5H3
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InChIKey |
UXTFTMXAFOTATJ-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Phosphodiesterase 1B (PDE1B) | Target Info | Inhibitor | [1] |
Target's Patent Info | Phosphodiesterase 1B (PDE1B) | Target's Patent Info | [1] | |
KEGG Pathway | Purine metabolism | |||
Calcium signaling pathway | ||||
Morphine addiction | ||||
Reactome | cGMP effects | |||
G alpha (s) signalling events | ||||
WikiPathways | G Protein Signaling Pathways | |||
DAG and IP3 signaling | ||||
Opioid Signalling |
References | Top | |||
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REF 1 | 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors. US10034861. |
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