Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00CKV
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| Drug Name |
Indolizine derivative 1
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| Synonyms |
PMID27718763-Compound-5
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| Drug Type |
Small molecular drug
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H16F3NO2
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| Canonical SMILES |
CC(=O)C1=C(C(=C2N1C=CC=C2)C(=O)C3=CC=C(C=C3)C(F)(F)F)C4=CC=CC=C4
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| InChI |
1S/C24H16F3NO2/c1-15(29)22-20(16-7-3-2-4-8-16)21(19-9-5-6-14-28(19)22)23(30)17-10-12-18(13-11-17)24(25,26)27/h2-14H,1H3
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| InChIKey |
GLIRMGCILWOVQU-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 15-lipoxygenase (15-LOX) | Target Info | Inhibitor | [1] |
| Platelet-activating factor acetylhydrolase (PLA2G7) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | Arachidonate 15-lipoxygenase (15-LOX) | Target's Patent Info | [1] | |
| Platelet-activating factor acetylhydrolase (PLA2G7) | Target's Patent Info | [1] | ||
| BioCyc | Resolvin D biosynthesis | |||
| Lipoxin biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Linoleic acid metabolism | ||||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ether lipid metabolism | ||||
| Biosynthesis of antibiotics | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| Lissencephaly gene (LIS1) in neuronal migration and development | ||||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| IL1 and megakaryotyces in obesity | ||||
| Synthesis, Secretion, and Deacylation of Ghrelin | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibitors of phospholipase A2 and their therapeutic potential: an update on patents (2012-2016).Expert Opin Ther Pat. 2017 Feb;27(2):217-225. | |||
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