| Patent(s) and the Corresponding Patented Drug(s) |
Top |
| World Intellectual Property Organization (WIPO) |
| Patent ID |
WO2014114694 |
| Title |
2,3-Dihydroimidazol[1,2-C]Pyrimidin-5(1H)-One Based Lipoprotein-Associated Phospholipase A2 (Lp-Pla2) Inhibitors. |
| Abstract |
The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease. |
| Applicant(s) |
Glaxosmithkline Intellectual Property Development Limited |
| Representative Drug(s) |
D0N8BA |
Drug Info
|
pIC50 = 11 |
[1] |
| Patent ID |
WO2015048177 |
| Title |
Long Shelf-Life Kits and Methods for Standardizing, Verifying, Calibrating or Recalibrating Lipoprotein- Associated Phospholipase A2 Detection. |
| Abstract |
Value-assigned solutions having predetermined concentrations of recombinant Lp-PLA2 are described herein. In particular, described herein are solutions of rLp-PLA2 that are stable for an extended period of time. Kits and assays include these calibration solutions, as well as methods of making and using them are described. Also described herein are Long shelf-life kits, value-assigned solutions, and methods for standardizing, verifying, calibrating or recalibrating detection of lipoprotein-associated phospholipase A2 having using them. In particular, described herein are methods of using solutions of rLp-PLA2 that are stable for an extended period of time to standardize, verify, calibrate or recalibrate assays for Lp-PLA2. |
| Applicant(s) |
Diadexus, Inc |
| United States Patent and Trademark Office (USPTO) |
| Patent ID |
US20150094331 |
| Title |
Quinolone Inhibitors of Lipoprotein-Associated Phospholipase A2. |
| Applicant(s) |
Auspex Pharmaceuticals Inc |
| Patent ID |
US20150025105 |
| Title |
Indolizine Derivatives. |
| Representative Drug(s) |
D00CKV |
Drug Info
|
N.A. |
[1] |
| Patent ID |
US20140107135 |
| Title |
Pyrimidinone Inhibitors of Lipoprotein-Associated Phospholipase A2. |
| Applicant(s) |
Auspex Pharmaceutics Inc |
| Patent ID |
US2015353986 |
| Title |
Methods for Treatment of Coronary Heart Disease Events Based of Lipoprotein-Associated Phospholipase A2Activity. |
| Patent ID |
US20150203590 |
| Title |
Lipoprotein-Associated Phospholipase A2Antibody Compositions and Methods of Use. |
| Patent ID |
US20130236450 |
| Title |
Methods Using Lipoprotein-Associated Phospholipase A2In An Acute Care Setting. |
