| Patent(s) and the Corresponding Patented Drug(s) |
Top |
| World Intellectual Property Organization (WIPO) |
| Patent ID |
WO9932433 |
| Title |
Thiourea and Benzamide Compounds,Compositions and Methods of Treating or Preventing Inflammatory Diseases and Atherosclerosis. |
| Representative Drug(s) |
D0GL1X |
Drug Info
|
IC50 = 10 nM |
[1] |
| Patent ID |
WO9712615 |
| Title |
Benzimidazol Derivatives As 15-Lox InhiBitors. |
| Representative Drug(s) |
D00NVU |
Drug Info
|
IC50 = 96 nM |
[1] |
| Patent ID |
WO9638144 |
| Title |
Isothiazolones. |
| Representative Drug(s) |
D09ZAJ |
Drug Info
|
IC50 = 120 nM |
[1] |
| Patent ID |
WO0196336 |
| Title |
5,6-Fussed Bicyclic Heterocycles. |
| Representative Drug(s) |
D0IA4F |
Drug Info
|
IC50 = 10000 nM |
[1] |
| Patent ID |
WO0196298 |
| Title |
1,2,4-Trisubstituted Benzene As Inhibitors of 15-Lipoxygenase. |
| Representative Drug(s) |
D0OW2D |
Drug Info
|
IC50(human 15-LOX) = 5 nM |
[1] |
| Patent ID |
WO2004080999 |
| Title |
Pyrazole Compounds Useful In The Treatment of Inflammation. |
| Abstract |
There is provided a compound of formula (I), wherein R1, R2, R3, X and Y have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation. |
| Applicant(s) |
Biolipox Ab Mcneeney, et al |
| Patent ID |
WO9712613 |
| Title |
Method for Treating and Preventing Inflammation and Atherosclerosis. |
| United States Patent and Trademark Office (USPTO) |
| Patent ID |
US3388133 |
| Title |
Benz[B]Indolo[2,3-D] Thiopyrylium Compounds and Processes for Their Production. |
| Applicant(s) |
WARNER LAMBERT PHARMACEUTICAL |
| Patent ID |
US20090186918 |
| Title |
Triazole Compounds As Lipoxygenase Inhibitors. |
| Representative Drug(s) |
D09AXR |
Drug Info
|
IC50 = 330 nM |
[1] |
| Patent ID |
US6858739 |
| Title |
Indole and Benzimidazole 15- LipoxygenAse Inhibitors. |
| Representative Drug(s) |
D02AAR |
Drug Info
|
N.A. |
[1] |
| Patent ID |
US4797495 |
| Title |
Benzo[C] Carbazole Propanediol Compound and Salts Thereof. |
| Patent ID |
US4132714 |
| Title |
Production of ChromenoinDole Compounds. |
| Patent ID |
US3853908 |
| Title |
1-Amino-Sulfonyl-2-Amino Benzimidazoles. |
| Patent ID |
US3682952 |
| Title |
5(6)-N-Butyl-2-CarBomethoxy-Benzimidazole. |
