Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09PWX
|
|||
| Former ID |
DNC004667
|
|||
| Drug Name |
Carzenide
|
|||
| Synonyms |
Para-Carboxybenzenesulfonamide (Weak Carbonic Anhydrase Inhibitor)
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C7H7NO4S
|
|||
| Canonical SMILES |
C1=CC(=CC=C1C(=O)O)S(=O)(=O)N
|
|||
| InChI |
1S/C7H7NO4S/c8-13(11,12)6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)
|
|||
| InChIKey |
UCAGLBKTLXCODC-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 138-41-0
|
|||
| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. J Med Chem. 2009 Feb 12;52(3):646-54. | |||
| REF 2 | Ligand-directed tosyl chemistry for protein labeling in vivo. Nat Chem Biol. 2009 May;5(5):341-3. | |||
| REF 3 | Synthesis and structure-activity relationships of novel benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5429-33. | |||
| REF 4 | Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglauc... Bioorg Med Chem Lett. 2005 Feb 15;15(4):963-9. | |||
| REF 5 | Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides. Bioorg Med Chem Lett. 2005 Sep 1;15(17):3828-33. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.