Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T10147 Target Info
Target Name Protein-tyrosine phosphatase sigma (R-PTP-sigma)
Synonyms
Receptor-type tyrosine-protein phosphatase sigma; Receptor-type tyrosine-protein phosphatase S; R-PTP-S
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Target Type Successful Target
Gene Name PTPRS
Biochemical Class Phosphoric monoester hydrolase
UniProt ID
PTPRS_HUMAN
Co-Targets of This Target  Top
Co-Target Name Escherichia coli Type IV secretion-like conjugative transfer relaxase protein TraI (Ecoli traI) Co-Target
UniProt ID B1LRJ1_ECOSM
Gene Name Ecoli traI
Representative Drug(s) Etidronic acid Drug Info Ki = 3 nM [1]
References  Top
REF 1 Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase. Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12282-7.

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