Target Validation Information
Target ID T72515
Target Name Interleukin 1 receptor
Target Type
Successful
Drug Potency against Target Anakinra Drug Info IC50 = 1.935 nM [553085]
References
Ref 553085IL-1 receptor accessory protein-Ig/IL-1 receptor type II-Ig heterodimer inhibits IL-1 response more strongly than other IL-1 blocking biopharmaceutical agents. J Clin Immunol. 2011 Jun;31(3):455-64. doi: 10.1007/s10875-010-9497-z. Epub 2010 Dec 22.

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