Target Validation Information | |||||
---|---|---|---|---|---|
Target ID | T72515 | ||||
Target Name | Interleukin 1 receptor | ||||
Target Type | Successful |
||||
Drug Potency against Target | Anakinra | Drug Info | IC50 = 1.935 nM | [553085] | |
References | |||||
Ref 553085 | IL-1 receptor accessory protein-Ig/IL-1 receptor type II-Ig heterodimer inhibits IL-1 response more strongly than other IL-1 blocking biopharmaceutical agents. J Clin Immunol. 2011 Jun;31(3):455-64. doi: 10.1007/s10875-010-9497-z. Epub 2010 Dec 22. |
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