Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02DES
|
||||
| Former ID |
DAP000095
|
||||
| Drug Name |
Anakinra
|
||||
| Synonyms |
Kineret; Kineret (TN); Anakinra (USAN/INN)
|
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| Therapeutic Class |
Antiinflammatory Agents
|
||||
| Company |
Amgen Inc
|
||||
| Formula |
C759H1186N208O232S10
|
||||
| CAS Number |
CAS 143090-92-0
|
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| PubChem Substance ID | |||||
| SuperDrug ATC ID |
L04AC03
|
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| Target and Pathway | |||||
| Target(s) | Interleukin 1 receptor | Target Info | Antagonist | [536369], [537496] | |
| PANTHER Pathway | p38 MAPK pathway | ||||
| Pathway Interaction Database | IL12-mediated signaling events | ||||
| IL1-mediated signaling events | |||||
| Reactome | Interleukin-1 signaling | ||||
| WikiPathways | Monoamine Transport | ||||
| Hypertrophy Model | |||||
| MAPK Signaling Pathway | |||||
| IL1 and megakaryotyces in obesity | |||||
| Structural Pathway of Interleukin 1 (IL-1) | |||||
| Spinal Cord Injury | |||||
| Integrated Pancreatic Cancer Pathway | |||||
| IL-1 signaling pathway | |||||
| Interleukin-1 signaling | |||||
| Apoptosis Modulation and Signaling | |||||
| Serotonin Transporter Activity | |||||
| References | |||||
| Ref 536711 | Molecular targets of rheumatoid arthritis. Inflamm Allergy Drug Targets. 2008 Mar;7(1):53-66. | ||||
| Ref 542003 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6972). | ||||
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