MAP kinase p38 beta; Mitogen-activated protein kinase p38 beta; P38 Mitogen-activated protein kinase beta; P38-2; P38b; Stress-activated protein kinase-2; MAPK11
Target Type
Clinical Trial
Disease
Psoriasis [ICD9: 696; ICD10: L40]
Function
Kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. Phosphorylates preferentially transcription factor atf2.
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