Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T52969
|
||||
| Former ID |
TTDR00281
|
||||
| Target Name |
CAP-dependent endonuclease
|
||||
| Target Type |
Discontinued
|
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| Drugs and Mode of Action | |||||
| Drug(s) | Flutimide | Drug Info | Terminated | Discovery agent | [1] |
| Inhibitor | 4-substituted 2,4-dioxobutanoic acids | Drug Info | [2] | ||
| Flutimide | Drug Info | [3] | |||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006184) | ||||
| REF 2 | Anti-influenza virus activities of 4-substituted 2,4-dioxobutanoic acid inhibitors. Antimicrob Agents Chemother. 1996 May;40(5):1304-7. | ||||
| REF 3 | Synthesis of natural flutimide and analogous fully substituted pyrazine-2,6-diones, endonuclease inhibitors of influenza virus. J Org Chem. 2001 Aug 10;66(16):5504-16. | ||||
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