Drug General Information
Drug ID
D0U5PR
Former ID
DIB011241
Drug Name
Seridopidine
Synonyms
ACR-343
Drug Type
Small molecular drug
Indication Neurological disease [ICD9: 338, 338.2, 410, 782.3,780; ICD10:I21, I22, R52, R52.1-R52.2, R60.9, G89] Terminated [546992]
Company
A Carlsson Research AB
Structure
Download
2D MOL

3D MOL

Formula
C14H20FNO2S
Canonical SMILES
c1c(cc(cc1S(=O)(=O)C)C1CCN(CC1)CC)F
CAS Number
CAS 883631-51-4
PubChem Compound ID
Target and Pathway
Target(s) Sodium-dependent dopamine transporter Target Info Modulator [533284]
KEGG Pathway Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Amphetamine addiction
Alcoholism
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
Parkinson disease
Dopamine receptor mediated signaling pathway
Pathway Interaction Database Alpha-synuclein signaling
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Dopaminergic Neurogenesis
Parkinsons Disease Pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
Neurotransmitter Clearance In The Synaptic Cleft
References
Ref 546992Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011877)
Ref 533284Pridopidine selectively occupies sigma-1 rather than dopamine D2 receptors at behaviorally active doses. Psychopharmacology (Berl). 2015 Sep;232(18):3443-53.

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