Drug Information
Drug General Information | |||||
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Drug ID |
D0V7HI
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Former ID |
DIB007048
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Drug Name |
PRINOMIDE TROMETHAMINE
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Synonyms |
3-(1-Methylpyrrol-2-yl)-3-oxo-2-(N-phenylcarbamoyl)propionitrile tromethamine salt
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Drug Type |
Small molecular drug
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Indication | Inflammation [ICD10:E08-E13, E10.2, E11, E11.2, E13.2, I73.9, I80-I82, N00-N29, G89] | Discontinued in Phase 3 | [544513] | ||
Structure |
Download2D MOL |
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Formula |
C19H24N4O5
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Canonical SMILES |
Cn1cccc1C(=O)C(C#N)C(=O)Nc2ccccc2.NC(CO)(CO)CO
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InChI |
1S/C15H13N3O2.C4H11NO3/c1-18-9-5-8-13(18)14(19)12(10-16)15(20)17-11-6-3-2-4-7-11;5-4(1-6,2-7)3-8/h2-9,12H,1H3,(H,17,20);6-8H,1-3,5H2
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InChIKey |
CPUJDORGQAJDCT-UHFFFAOYSA-N
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CAS Number |
CAS 109636-76-2
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Prostaglandin G/H synthase 2 | Target Info | Inhibitor | [526385], [551871] | |
KEGG Pathway | Arachidonic acid metabolism | ||||
Metabolic pathways | |||||
NF-kappa B signaling pathway | |||||
VEGF signaling pathway | |||||
TNF signaling pathway | |||||
Retrograde endocannabinoid signaling | |||||
Serotonergic synapse | |||||
Ovarian steroidogenesis | |||||
Oxytocin signaling pathway | |||||
Regulation of lipolysis in adipocytes | |||||
Leishmaniasis | |||||
Pathways in cancer | |||||
Chemical carcinogenesis | |||||
MicroRNAs in cancer | |||||
Small cell lung cancer | |||||
PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
References |
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