Drug Information
Drug General Information | |||||
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Drug ID |
D0EJ9B
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Former ID |
DNC005114
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Drug Name |
Phenyl Boronic acid
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Synonyms |
Phenylboronic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [530358] | ||
Structure |
Download2D MOL |
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Formula |
C6H7BO2
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Canonical SMILES |
B(C1=CC=CC=C1)(O)O
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InChI |
1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
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InChIKey |
HXITXNWTGFUOAU-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | D-alanyl-D-alanine carboxypeptidase | Target Info | Inhibitor | [530358] | |
Carbonic anhydrase II | Target Info | Inhibitor | [527231] | ||
Carbonic anhydrase IV | Target Info | Inhibitor | [529905] | ||
Carbonic anhydrase | Target Info | Inhibitor | [528141] | ||
Fatty-acid amide hydrolase | Target Info | Inhibitor | [529790] | ||
Carbonic anhydrase I | Target Info | Inhibitor | [527231] | ||
BioCyc Pathway | Anandamide degradation | ||||
KEGG Pathway | Nitrogen metabolism | ||||
Proximal tubule bicarbonate reclamation | |||||
Collecting duct acid secretion | |||||
Gastric acid secretion | |||||
Pancreatic secretion | |||||
Bile secretionhsa00910:Nitrogen metabolism | |||||
Proximal tubule bicarbonate reclamationhsa04723:Retrograde endocannabinoid signalinghsa00910:Nitrogen metabolism | |||||
NetPath Pathway | IL4 Signaling Pathway | ||||
EGFR1 Signaling Pathway | |||||
PANTHER Pathway | Anandamide degradation | ||||
Pathway Interaction Database | C-MYB transcription factor network | ||||
PathWhiz Pathway | Gastric Acid Production | ||||
References | |||||
Ref 527231 | Bioorg Med Chem Lett. 2004 Nov 1;14(21):5435-9.Carbonic anhydrase inhibitors. Inhibition of the newly isolated murine isozyme XIII with anions. | ||||
Ref 528141 | Bioorg Med Chem Lett. 2006 Jun 15;16(12):3139-43. Epub 2006 Apr 18.Carbonic anhydrase inhibitors: inhibition of the cytosolic human isozyme VII with anions. | ||||
Ref 529790 | J Med Chem. 2008 Nov 27;51(22):7057-60.Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase. | ||||
Ref 529905 | Bioorg Med Chem Lett. 2009 Feb 15;19(4):1155-8. Epub 2008 Dec 25.Carbonic anhydrase inhibitors: the membrane-associated isoform XV is highly inhibited by inorganic anions. | ||||
Ref 530358 | J Med Chem. 2009 Oct 8;52(19):6097-106.Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors. |
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