Drug Information
Drug General Information | |||||
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Drug ID |
D0KG1D
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Former ID |
DNC008426
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Drug Name |
2-(3-hydroxyphenyl)quinolin-6-ol
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [529359] | ||
Structure |
Download2D MOL |
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Formula |
C15H11NO2
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Canonical SMILES |
C1=CC(=CC(=C1)O)C2=NC3=C(C=C2)C=C(C=C3)O
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InChI |
1S/C15H11NO2/c17-12-3-1-2-10(8-12)14-6-4-11-9-13(18)5-7-15(11)16-14/h1-9,17-18H
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InChIKey |
KVSLALXAPWSPAG-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Estradiol 17 beta-dehydrogenase 1 | Target Info | Inhibitor | [529359] | |
NetPath Pathway | FSH Signaling Pathway | ||||
PANTHER Pathway | Androgen/estrogene/progesterone biosynthesis | ||||
PathWhiz Pathway | Androgen and Estrogen Metabolism | ||||
References | |||||
Ref 529359 | J Med Chem. 2008 Apr 10;51(7):2158-69. Epub 2008 Mar 7.Design, synthesis, and biological evaluation of (hydroxyphenyl)naphthalene and -quinoline derivatives: potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases. | ||||
Ref 529359 | J Med Chem. 2008 Apr 10;51(7):2158-69. Epub 2008 Mar 7.Design, synthesis, and biological evaluation of (hydroxyphenyl)naphthalene and -quinoline derivatives: potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases. |
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