Drug General Information
Drug ID	D06GFV
Former ID	DNC011525
Drug Name	1-(2,3-Dihydro-1H-indol-5-ylmethyl)-propylamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533479]
Structure		Download 2D MOL 3D MOL
Formula	C12H18N2
Canonical SMILES	CCC(CC1=CC2=C(C=C1)NCC2)N
InChI	1S/C12H18N2/c1-2-11(13)8-9-3-4-12-10(7-9)5-6-14-12/h3-4,7,11,14H,2,5-6,8,13H2,1H3
InChIKey	WHXRWSJORCUAFO-UHFFFAOYSA-N
PubChem Compound ID	13660291
Target and Pathway
Target(s)	Sodium-dependent dopamine transporter	Target Info	Inhibitor	[533479]
	Sodium-dependent noradrenaline transporter	Target Info	Inhibitor	[533479]
KEGG Pathway	Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Amphetamine addiction
	Alcoholism
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
	Parkinson disease
	Dopamine receptor mediated signaling pathwayP00001:Adrenaline and noradrenaline biosynthesis
Pathway Interaction Database	Alpha-synuclein signaling
Reactome	Na+/Cl- dependent neurotransmitter transportersR-HSA-442660:Na+/Cl- dependent neurotransmitter transporters
WikiPathways	Monoamine Transport
	NRF2 pathway
	Dopaminergic Neurogenesis
	Parkinsons Disease Pathway
	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
	Neurotransmitter Clearance In The Synaptic CleftWP727:Monoamine Transport
References
Ref 533479	J Med Chem. 1986 Aug;29(8):1406-12.Selective monoamine oxidase inhibitors. 3. Cyclic compounds related to 4-aminophenethylamine. Preparation and neuron-selective action of some 5-(2-aminoethyl)-2,3-dihydroindoles.
Ref 533479	J Med Chem. 1986 Aug;29(8):1406-12.Selective monoamine oxidase inhibitors. 3. Cyclic compounds related to 4-aminophenethylamine. Preparation and neuron-selective action of some 5-(2-aminoethyl)-2,3-dihydroindoles.

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