Drug Information

Drug General Information
Drug ID
D07CQD
Former ID
DNC009000
Drug Name
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529569]
Structure
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2D MOL

3D MOL
Formula
C19H25NS
Canonical SMILES
C1CCC(CC1)(C2=CC3=CC=CC=C3S2)N4CCCCC4
InChI
1S/C19H25NS/c1-5-11-19(12-6-1,20-13-7-2-8-14-20)18-15-16-9-3-4-10-17(16)21-18/h3-4,9-10,15H,1-2,5-8,11-14H2
InChIKey
RGSVXQJPSWZXOP-UHFFFAOYSA-N
PubChem Compound ID
123692
Target and Pathway
Target(s) Sodium-dependent dopamine transporter Target Info Inhibitor [529569]
KEGG Pathway Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Amphetamine addiction
Alcoholism
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
Parkinson disease
Dopamine receptor mediated signaling pathway
Pathway Interaction Database Alpha-synuclein signaling
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Dopaminergic Neurogenesis
Parkinsons Disease Pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
Neurotransmitter Clearance In The Synaptic Cleft
References
Ref 529569J Med Chem. 2008 Jul 24;51(14):4150-69. Epub 2008 Jun 28.Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
Ref 529569J Med Chem. 2008 Jul 24;51(14):4150-69. Epub 2008 Jun 28.Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.

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