Drug Information
Drug General Information | |||||
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Drug ID |
D0C0JT
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Former ID |
DNC003303
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Drug Name |
Nimesulide
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C13H12N2O5S
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InChI |
InChI=1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3
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InChIKey |
HYWYRSMBCFDLJT-UHFFFAOYSA-N
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CAS Number |
CAS 51803-78-2
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PubChem Compound ID | |||||
PubChem Substance ID |
855635, 5912186, 6436673, 7404099, 7848112, 7889413, 7980127, 8149946, 8152768, 10321585, 11111520, 11111521, 11121727, 11122207, 11335868, 11361107, 11362857, 11364471, 11365419, 11367033, 11367981, 11369595, 11370925, 11370926, 11372711, 11373582, 11373834, 11376143, 11377757, 11462079, 11466222, 11467342, 11485118, 11485804, 11489357, 11491391, 11491993, 11495391, 12012650, 14752054, 17405416, 24277576, 24278583, 26612437, 26680139, 26697157, 26746940, 26746941, 26751468, 29215000
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SuperDrug ATC ID |
M01AX17; M02AA26
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Target and Pathway | |||||
Target(s) | Prostaglandin G/H synthase 2 | Target Info | Inhibitor | [551378] | |
Lactotransferrin | Target Info | Inhibitor | [551378] | ||
KEGG Pathway | Arachidonic acid metabolism | ||||
Metabolic pathways | |||||
NF-kappa B signaling pathway | |||||
VEGF signaling pathway | |||||
TNF signaling pathway | |||||
Retrograde endocannabinoid signaling | |||||
Serotonergic synapse | |||||
Ovarian steroidogenesis | |||||
Oxytocin signaling pathway | |||||
Regulation of lipolysis in adipocytes | |||||
Leishmaniasis | |||||
Pathways in cancer | |||||
Chemical carcinogenesis | |||||
MicroRNAs in cancer | |||||
Small cell lung cancer | |||||
PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
WikiPathways | Prostaglandin Synthesis and Regulation | ||||
Arachidonic acid metabolism | |||||
Aryl Hydrocarbon Receptor | |||||
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | |||||
Spinal Cord Injury | |||||
Integrated Pancreatic Cancer Pathway | |||||
Eicosanoid Synthesis | |||||
Selenium Micronutrient NetworkWP2700:Latent infection of Homo sapiens with Mycobacterium tuberculosis | |||||
References | |||||
Ref 523284 | ClinicalTrials.gov (NCT01257126) Efficacy of Diclofenac Potassium vs Nimesulide in the Treatment of Fever and Pain in Children With Upper Respiratory Tract Infection. U.S. National Institutes of Health. | ||||
Ref 542424 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7401). |
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