Drug General Information
Drug ID	D06CMJ
Former ID	DNC010640
Drug Name	Para-chloroamphetamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[467832]
Structure		Download 2D MOL 3D MOL
Formula	C9H12ClN
InChI	InChI=1S/C9H12ClN/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5,7H,6,11H2,1H3
InChIKey	WWPITPSIWMXDPE-UHFFFAOYSA-N
PubChem Compound ID	3127
PubChem Substance ID	144422, 3221185, 7646846, 7980249, 8151993, 11406747, 15437689, 29222269, 30369885, 49880045, 50065008, 57321628, 75126043, 89084752, 99300564, 103392557, 103843885, 103938193, 104302600, 104706350, 117463198, 126407537, 129644874, 131324646, 134347845, 134971965, 135176785, 137009698, 142324085, 162210641, 162223123, 162889059, 170539229, 174534479, 177348006, 178101313, 179688084, 215795823, 221672779, 224007800, 226614389, 241108764, 249550220, 249911618
Target and Pathway
Target(s)	Sodium-dependent serotonin transporter	Target Info	Inhibitor	[530347]
	Sodium-dependent dopamine transporter	Target Info	Inhibitor	[530347]
	Sodium-dependent noradrenaline transporter	Target Info	Inhibitor	[530347]
KEGG Pathway	Serotonergic synapsehsa04728:Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Amphetamine addiction
	Alcoholism
NetPath Pathway	TCR Signaling Pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
	5HT2 type receptor mediated signaling pathway
	5HT3 type receptor mediated signaling pathway
	5HT4 type receptor mediated signaling pathwayP00001:Adrenaline and noradrenaline biosynthesis
	Parkinson disease
	Dopamine receptor mediated signaling pathwayP00001:Adrenaline and noradrenaline biosynthesis
Pathway Interaction Database	Alpha-synuclein signaling
Reactome	Na+/Cl- dependent neurotransmitter transportersR-HSA-442660:Na+/Cl- dependent neurotransmitter transporters
WikiPathways	Monoamine Transport
	SIDS Susceptibility Pathways
	NRF2 pathway
	Synaptic Vesicle Pathway
	Serotonin Transporter ActivityWP727:Monoamine Transport
	Dopaminergic Neurogenesis
	Parkinsons Disease Pathway
	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
	Neurotransmitter Clearance In The Synaptic CleftWP727:Monoamine Transport
References
Ref 467832	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4592).
Ref 530347	Eur J Med Chem. 2009 Dec;44(12):4862-88. Epub 2009 Aug 6.Synthesis and serotonin transporter activity of sulphur-substituted alpha-alkyl phenethylamines as a new class of anticancer agents.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.