Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08PKR
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| Former ID |
DNC004476
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| Drug Name |
6-Imidazol-1-yl-isoquinoline
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| Synonyms |
6-(1H-imidazol-1-yl)isoquinoline
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [525760] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C12H9N3
|
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| Canonical SMILES |
C1=CC2=C(C=CN=C2)C=C1N3C=CN=C3
|
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| InChI |
1S/C12H9N3/c1-2-12(15-6-5-14-9-15)7-10-3-4-13-8-11(1)10/h1-9H
|
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| InChIKey |
YACWDKFXWATANA-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cytochrome P450 19 | Target Info | Inhibitor | [529860] | |
| Thromboxane-A synthase | Target Info | Inhibitor | [525760] | ||
| NetPath Pathway | FSH Signaling Pathway | ||||
| PANTHER Pathway | Androgen/estrogene/progesterone biosynthesis | ||||
| PathWhiz Pathway | Androgen and Estrogen MetabolismPW000044:Arachidonic Acid Metabolism | ||||
| Reactome | Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | ||||
| Tryptophan metabolism | |||||
| Oxidation by Cytochrome P450 | |||||
| Ovarian Infertility Genes | |||||
| Metabolism of steroid hormones and vitamin D | |||||
| FSH signaling pathway | |||||
| Integrated Breast Cancer Pathway | |||||
| Phase 1 - Functionalization of compoundsWP98:Prostaglandin Synthesis and Regulation | |||||
| Arachidonic acid metabolism | |||||
| Phase 1 - Functionalization of compounds | |||||
| Eicosanoid Synthesis | |||||
| References | |||||
| Ref 525760 | J Med Chem. 2000 May 4;43(9):1841-51.1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase. | ||||
| Ref 529860 | J Med Chem. 2009 Jan 8;52(1):143-50.Fast three dimensional pharmacophore virtual screening of new potent non-steroid aromatase inhibitors. | ||||
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