Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0W5DZ
|
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| Former ID |
DNC009194
|
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| Drug Name |
CHLOROPUUPEHENONE
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C21H27ClO3
|
||||
| Canonical SMILES |
CC1(CCCC2(C1CCC3(C2C=C4C(=CC(=O)C(=C4Cl)O)O3)C)C)C
|
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| InChI |
1S/C21H27ClO3/c1-19(2)7-5-8-20(3)15(19)6-9-21(4)16(20)10-12-14(25-21)11-13(23)18(24)17(12)22/h10-11,15-16,24H,5-9H2,1-4H3/t15-,16+,20-,21-/m0/s1
|
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| InChIKey |
IVURSJNKOFPQMR-GQSCTRQFSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Arachidonate 12-lipoxygenase, 12S-type | Target Info | Inhibitor | [1] | |
| Arachidonate 15-lipoxygenase | Target Info | Inhibitor | [1] | ||
| BioCyc Pathway | Lipoxin biosynthesisPWY66-397:Resolvin D biosynthesis | ||||
| Lipoxin biosynthesis | |||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channelshsa00590:Arachidonic acid metabolism | |||||
| Linoleic acid metabolism | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PANTHER Pathway | Inflammation mediated by chemokine and cytokine signaling pathwayP00031:Inflammation mediated by chemokine and cytokine signaling pathway | ||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| PathWhiz Pathway | Arachidonic Acid MetabolismPW000044:Arachidonic Acid Metabolism | ||||
| WikiPathways | Arachidonic acid metabolism | ||||
| Eicosanoid SynthesisWP2650:Arachidonic acid metabolism | |||||
| Eicosanoid Synthesis | |||||
| References | |||||
| REF 1 | J Nat Prod. 2003 Feb;66(2):230-5.Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. | ||||
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