Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09EMR
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| Former ID |
DNC006499
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| Drug Name |
Tyr-D-Phe-Gly-D-Trp-Nle-Asp-Phe-NH2
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [528193] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C50H59N9O10
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| Canonical SMILES |
CCCCC(C(=O)NC(CC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O<br />)C(CC2=CNC3=CC=CC=C32)NC(=O)CNC(=O)C(CC4=CC=CC=C4)NC(=O<br />)C(CC5=CC=C(C=C5)O)N
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| InChI |
1S/C50H59N9O10/c1-2-3-17-38(48(67)59-42(27-44(62)63)50(69)57-39(45(52)64)24-30-12-6-4-7-13-30)56-49(68)41(26-33-28-53-37-18-11-10-16-35(33)37)55-43(61)29-54-47(66)40(25-31-14-8-5-9-15-31)58-46(65)36(51)23-32-19-21-34(60)22-20-32/h4-16,18-22,28,36,38-42,53,60H,2-3,17,23-27,29,51H2,1H3,(H2,52,64)(H,54,66)(H,55,61)(H,56,68)(H,57,69)(H,58,65)(H,59,67)(H,62,63)/t36-,38-,39-,40+,41+,42-/m0/s1
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| InChIKey |
DWHRPZRXNRDAQF-KCTXSUAESA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Gastrin/cholecystokinin type B receptor | Target Info | Inhibitor | [528193] | |
| Mu-type opioid receptor | Target Info | Inhibitor | [528193] | ||
| Delta-type opioid receptor | Target Info | Inhibitor | [528193] | ||
| Cholecystokinin receptor type A | Target Info | Inhibitor | [528193] | ||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gastric acid secretionhsa04080:Neuroactive ligand-receptor interaction | |||||
| Estrogen signaling pathway | |||||
| Morphine addictionhsa04022:cGMP-PKG signaling pathway | |||||
| Sphingolipid signaling pathway | |||||
| Neuroactive ligand-receptor interactionhsa04020:Calcium signaling pathway | |||||
| Insulin secretion | |||||
| Pancreatic secretion | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | CCKR signaling map STP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin releaseP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| PathWhiz Pathway | Gastric Acid Production | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Secretion of Hydrochloric Acid in Parietal Cells | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, OtherWP69:TCR Signaling Pathway | |||||
| Opioid Signalling | |||||
| GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like | |||||
| References | |||||
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