Drug General Information
Drug ID	D02BXG
Former ID	DNC012290
Drug Name	1-Benzo[b]thiophen-2-yl-cyclohexylamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533891]
Structure		Download 2D MOL 3D MOL
Formula	C14H17NS
Canonical SMILES	C1CCC(CC1)(C2=CC3=CC=CC=C3S2)N
InChI	1S/C14H17NS/c15-14(8-4-1-5-9-14)13-10-11-6-2-3-7-12(11)16-13/h2-3,6-7,10H,1,4-5,8-9,15H2
InChIKey	HYVMNAZTYJDWIZ-UHFFFAOYSA-N
PubChem Compound ID	398415
Target and Pathway
Target(s)	Sodium-dependent dopamine transporter	Target Info	Inhibitor	[533891]
KEGG Pathway	Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Amphetamine addiction
	Alcoholism
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
	Parkinson disease
	Dopamine receptor mediated signaling pathway
Pathway Interaction Database	Alpha-synuclein signaling
Reactome	Na+/Cl- dependent neurotransmitter transporters
WikiPathways	Monoamine Transport
	NRF2 pathway
	Dopaminergic Neurogenesis
	Parkinsons Disease Pathway
	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
	Neurotransmitter Clearance In The Synaptic Cleft
References
Ref 533891	J Med Chem. 1993 Apr 30;36(9):1188-93.Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-binding sites.
Ref 533891	J Med Chem. 1993 Apr 30;36(9):1188-93.Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-binding sites.

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