Drug Information
Drug General Information | |||||
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Drug ID |
D02TMK
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Former ID |
DNC010642
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Drug Name |
METHYLENEDIOXYAMPHETAMINE
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [530914] | ||
Structure |
Download2D MOL |
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Formula |
C10H13NO2
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Canonical SMILES |
CC(CC1=CC2=C(C=C1)OCO2)N
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InChI |
1S/C10H13NO2/c1-7(11)4-8-2-3-9-10(5-8)13-6-12-9/h2-3,5,7H,4,6,11H2,1H3
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InChIKey |
NGBBVGZWCFBOGO-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Sodium-dependent noradrenaline transporter | Target Info | Inhibitor | [530914] | |
Sodium-dependent serotonin transporter | Target Info | Inhibitor | [530347] | ||
Sodium-dependent dopamine transporter | Target Info | Inhibitor | [530914] | ||
NetPath Pathway | TCR Signaling Pathway | ||||
PANTHER Pathway | Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway | ||||
5HT2 type receptor mediated signaling pathway | |||||
5HT3 type receptor mediated signaling pathway | |||||
5HT4 type receptor mediated signaling pathwayP00001:Adrenaline and noradrenaline biosynthesis | |||||
Parkinson disease | |||||
Dopamine receptor mediated signaling pathway | |||||
Pathway Interaction Database | Alpha-synuclein signaling | ||||
WikiPathways | Monoamine Transport | ||||
NRF2 pathway | |||||
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport | |||||
SIDS Susceptibility Pathways | |||||
Synaptic Vesicle Pathway | |||||
Serotonin Transporter ActivityWP727:Monoamine Transport | |||||
Dopaminergic Neurogenesis | |||||
Parkinsons Disease Pathway | |||||
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | |||||
Neurotransmitter Clearance In The Synaptic Cleft | |||||
References | |||||
Ref 530347 | Eur J Med Chem. 2009 Dec;44(12):4862-88. Epub 2009 Aug 6.Synthesis and serotonin transporter activity of sulphur-substituted alpha-alkyl phenethylamines as a new class of anticancer agents. | ||||
Ref 530914 | Bioorg Med Chem. 2010 Jun 1;18(11):4009-31. Epub 2010 Apr 13.Synthesis and in vitro toxicity of 4-MTA, its characteristic clandestine synthesis byproducts and related sulfur substituted alpha-alkylthioamphetamines. |
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