Drug Information

Drug General Information
Drug ID
D0Z9GI
Former ID
DNC007319
Drug Name
1-[bis(4-chlorophenyl)methyl]-3-phenylthiourea
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527861]
Structure
Download
2D MOL

3D MOL
Formula
C20H16Cl2N2S
Canonical SMILES
C1=CC=C(C=C1)NC(=S)NC(C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl
InChI
1S/C20H16Cl2N2S/c21-16-10-6-14(7-11-16)19(15-8-12-17(22)13-9-15)24-20(25)23-18-4-2-1-3-5-18/h1-13,19H,(H2,23,24,25)
InChIKey
SYUQZYSPZLUEIG-UHFFFAOYSA-N
PubChem Compound ID
11552795
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Inhibitor [527861]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 527861J Med Chem. 2005 Nov 17;48(23):7486-90.1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.
Ref 527861J Med Chem. 2005 Nov 17;48(23):7486-90.1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.