Drug General Information
Drug ID	D0Z1OI
Former ID	DNC004519
Drug Name	3-(4-Amino-phenyl)-3-ethyl-pyrrolidine-2,5-dione
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533480]
Structure		Download 2D MOL 3D MOL
Formula	C12H14N2O2
Canonical SMILES	CCC1(CC(=O)NC1=O)C2=CC=C(C=C2)N
InChI	1S/C12H14N2O2/c1-2-12(7-10(15)14-11(12)16)8-3-5-9(13)6-4-8/h3-6H,2,7,13H2,1H3,(H,14,15,16)
InChIKey	QPJZAHJMZUCFMF-UHFFFAOYSA-N
PubChem Compound ID	124662
Target and Pathway
Target(s)	Cytochrome P450 19	Target Info	Inhibitor	[533480]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Estradiol biosynthesis II
	Estradiol biosynthesis I
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
	Ovarian steroidogenesis
NetPath Pathway	FSH Signaling Pathway
PANTHER Pathway	Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway	Androgen and Estrogen Metabolism
Reactome	Endogenous sterols
WikiPathways	Metapathway biotransformation
	Tryptophan metabolism
	Oxidation by Cytochrome P450
	Ovarian Infertility Genes
	Metabolism of steroid hormones and vitamin D
	FSH signaling pathway
	Integrated Breast Cancer Pathway
	Phase 1 - Functionalization of compounds
References
Ref 533480	J Med Chem. 1986 Apr;29(4):520-3.Synthesis and biochemical evaluation of analogues of aminoglutethimide based on phenylpyrrolidine-2,5-dione.
Ref 533480	J Med Chem. 1986 Apr;29(4):520-3.Synthesis and biochemical evaluation of analogues of aminoglutethimide based on phenylpyrrolidine-2,5-dione.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.