Drug Information

Drug General Information
Drug ID
D0Y7CI
Former ID
DNC001348
Drug Name
SNC-80
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538988]
Structure
Download
2D MOL

3D MOL
Formula
C28H39N3O2
InChI
InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1
InChIKey
KQWVAUSXZDRQPZ-UMTXDNHDSA-N
CAS Number
CAS 156727-74-1
PubChem Compound ID
123924
PubChem Substance ID
529434, 10240915, 11113691, 11442535, 14833255, 26751883, 29304095, 49876690, 75498274, 85788618, 91746426, 103175041, 103946292, 104419665, 124886943, 126671676, 128421771, 134222928, 135078669, 135651062, 135697536, 137166400, 142093555, 144204476, 152344284, 162022466, 164233713, 164765031, 170466880, 170485796, 223660400, 227013170, 241181876, 241377470, 252160122, 252216323
Target and Pathway
Target(s) Delta-type opioid receptor Target Info Agonist [534994], [535449]
KEGG Pathway cGMP-PKG signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin release
Opioid proenkephalin pathway
Opioid proopiomelanocortin pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 538988(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1611).
Ref 534994Antiparkinson potential of delta-opioid receptor agonists. Eur J Pharmacol. 2000 May 19;396(2-3):101-7.
Ref 535449Nonpeptidic delta-opioid receptor agonists reduce immobility in the forced swim assay in rats. Neuropsychopharmacology. 2002 Jun;26(6):744-55.

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