Drug Information

Drug General Information
Drug ID
D0X8FV
Former ID
DNC007990
Drug Name
N-isopropyl-5,6-dip-tolylpyrazine-2-carboxamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528851]
Structure
Download
2D MOL

3D MOL
Formula
C22H23N3O
Canonical SMILES
CC1=CC=C(C=C1)C2=NC=C(N=C2C3=CC=C(C=C3)C)C(=O)NC(C)C
InChI
1S/C22H23N3O/c1-14(2)24-22(26)19-13-23-20(17-9-5-15(3)6-10-17)21(25-19)18-11-7-16(4)8-12-18/h5-14H,1-4H3,(H,24,26)
InChIKey
IZKDGGVGSMLFPW-UHFFFAOYSA-N
PubChem Compound ID
44440708
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Inhibitor [528851]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 528851Bioorg Med Chem Lett. 2007 Jul 15;17(14):3978-82. Epub 2007 Apr 29.Discovery of pyrazine carboxamide CB1 antagonists: the introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series.
Ref 528851Bioorg Med Chem Lett. 2007 Jul 15;17(14):3978-82. Epub 2007 Apr 29.Discovery of pyrazine carboxamide CB1 antagonists: the introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.